What are the physiological functions of astaxanthin?


The important property of astaxanthin lies in its antioxidant properties, which is an excellent antioxidant. The strong antioxidant activity of astaxanthin is due to its ability to stabilize the membrane structure, reduce membrane permeability, and restrict the entry of peroxide promoters into cells. Protect important molecules in cells from oxidative damage. At the same time, astaxanthin may have the potential to become a pro-oxidant to induce oxidative stress. The conjugated double bond, the hydroxyl group and the unsaturated ketone group at the end of the conjugated double bond chain in the astaxanthin molecule. The hydroxyl group and the ketone group constitute α-hydroxy ketone. These structures have relatively active electronic effects and can Provide electrons to free radicals or attract unpaired electrons of free radicals, effectively quenching the highly oxidizing singlet active oxygen and other free radicals in the environment. Studies have shown that the ability to quench active oxygen increases with the increase in the number of conjugated double bonds. Astaxanthin has the strongest quenching ability. Its ability to quench molecular oxygen is better than β-carotene, which has the same structure. Vitamin E, α-carotene, lutein and lycopene are all high. The astaxanthin integrated into the membrane system inhibits lipid peroxidation through its protective effect on liposomes. It can also protect cells and DNA from oxidative damage, protect intracellular proteins, and enable cells to effectively metabolize. The protein inside functions better. This antioxidant effect is manifested in prolonging the time for low-density lipoprotein (LDL) to be oxidized, thereby reducing the occurrence of atherosclerosis.

In addition, experiments have shown that astaxanthin can increase antioxidant enzyme activity and protein expression. Different doses of astaxanthin can significantly increase the protein expression of peroxyhydrogenase and superoxide dismutase in animal cells, and its biological activity also has Significantly improved, and these substances play a better antioxidant effect in the body.

Anticancer effect
The investigation of the relationship between dietary carotenoid intake and cancer incidence or mortality showed that the total cancer incidence or mortality was significantly negatively correlated with carotenoid intake. Comparing the anti-tumor activities of various carotenoids, astaxanthin has the strongest effect. The anti-tumor activity of astaxanthin may be related to its signal transduction between cells, the induction of metabolizing enzymes for heterogeneous substances, and the regulation of immune response related to tumor cells. Studies have shown that astaxanthin can inhibit the mutagenic effects caused by aflatoxin B1, phenylpropionyl pyrene (BaP), diethyl nitrous acid (DEN), nitrosamines and cyclophosphamide. Astaxanthin can prevent tumors. It plays a role in different stages of tumor formation. For example, by inhibiting the production of putrescine, and reducing the concentration of free polyamines such as spermine and spermidine, reducing the formation of tumor-inducing substances; protecting the skin from UV damage through antioxidant effects, preventing skin photoaging and preventing skin cancer; By strengthening the connection ability between normal cells, the cells induced by carcinogens are placed in an expanded communication network, so that the normal cells are dominant, and the cancer cells are isolated, reducing the connection between the cancer cells, controlling their growth, and preventing tumor transformation ; Astaxanthin also has a strong inhibitory effect on the proliferation of cancer cells, and high concentrations of astaxanthin can kill tumor cells. Studies have found that astaxanthin can effectively control a variety of cancers, such as liver cancer, oral cancer, colorectal cancer, bladder cancer and breast cancer.

Boost immunity
Astaxanthin can significantly enhance the body's local and systemic immunity. Combining this immunomodulatory property with antioxidant properties, it plays an important role in preventing the occurrence and spread of diseases. Experiments have shown that carotenoids can slow down the decline in immunity caused by aging, improve the function of the body's immune organs, and enhance resistance to harsh environments. More importantly, astaxanthin can enhance the function of T cells in the body, increase the number of neutrophils and natural killer cells, and participate in the body's cellular immunity; astaxanthin can also increase the vitality of B cells in the immune system and eliminate foreign invasions. The pathogens of the disease play a role by assisting in the production of antibodies and enhancing the activity of other immune components, such as promoting the production of immunoglobulin, increasing IgG (immunoglobulin G), IgA (immunoglobulin A) and IgM (immunoglobulin M) The amount of production, enhance the humoral immune response ability, and improve the immunity of animals.

Carotenoids are the main pigments in aquatic animals, and astaxanthin accounts for most of the carotenoids in aquatic animals. Therefore, it can be said that astaxanthin is the main pigment in aquatic animals. Astaxanthin is the end point of carotenoid synthesis. After entering the animal body, it can be directly stored in the tissue without modification or biochemical transformation. It has a strong pigment deposition ability, which makes the skin and muscles of some aquatic animals healthy and bright. The color makes the eggs and feathers, skins, feet and items of birds appear healthy golden or red. Experiments show that adding astaxanthin to the feed not only makes the fish's epidermal phosphorous yellow, but also increases the content of astaxanthin in the muscles.

Zhejiang Tianhecheng Bio-technology Shares Co., Ltd.. is a professional China Astaxanthin Manufacturers and Astaxanthin Factory, which committed to the production of vitamin series, polyunsaturated fatty acid series, carotenoid series and other(encapsulated) products. The company operates strictly in accordance with ISO9001 quality system and ISO22000 food safety system, adopts advanced nano-technology, spray drying process and double encapsulation process. It is a diversified large-scale professional production base in China. It integrates micro-powders, micro-particles, Product, and is based on the low, medium and high market. The capacity of the factory is around 2000 tons of micro-powder products, 300 tons of micro-particle products and more than 100 tons of liquid vitamins. The products export globally and most of the customers are related to healthy products, baked food, pet food and functional beverages.