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Does Lutein Have Any Side Effects?

Update:22-04-2022

In the known scientific literature, lutein is extremely safe when used in moderation. In the 5-year AREDS2 large-scale study, at a daily dose of 10 mg, no toxicity or adverse reactions have been found with Lutein and zeaxanthin.

The only confirmed side effect is yellowing of the skin of hands and feet (due to prolonged high dose or overdose, also known as carotenemia), which is caused by the fact that the body is more sensitive to lutein, and the skin is yellowed due to insufficient metabolism. I thought it was jaundice

Caroteneemia is harmless to the human body. As long as the intake is reduced, the yellowing of the skin will gradually subside, so there is no need to worry too much.
Safety Precautions (5 Points of Use Taboo)
1. The safety of using lutein during pregnancy and lactation is unknown, so it is recommended to consume more vegetables and fruits.

2. Cystic fibrosis patients often cannot successfully absorb carotenoids in food or supplements, so they should pay attention when using lutein products

3. Concomitant consumption of snacks containing alternative oils (Olestra) or use of other carotenoid supplements may reduce lutein absorption

4. A case study has identified a case of retinal crystal deposits in a woman with glaucoma who took long-term lutein (20 mg daily for 8 years with a high lutein diet) , and this phenomenon did not affect the patient's vision, and the crystals had partially disappeared after discontinuation.

5. Smokers taking high-dose lutein supplements (daily doses greater than 10 mg) may be associated with a higher risk of lung cancer, so caution should be used before use.